2021

Superconductivity

Superconductivity: Past, Present and Future

Figure 1: Dutch physicist Heike Kamerlingh Onnes. Onnes lay the foundations for the field of superconductivity. He was able to liquefy Helium down to a temperature of 0.9K (-272 °C), enabling him to discover superconductivity in mercury. The liquefication of Helium enabled him to discover superconductivity in mercury at a very low temperature which was …

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Bispecific Antibody Recruits Vγ9+ γδ T cells for Leukemia Treatment

Bispecific Antibody Recruits Vγ9+ γδ T cells for Leukemia Treatment

Figure 1: The image is taken from an elderly woman who has a type of acute myeloid leukemia in which the accumulation of immature blood-forming cells (purple) interferes with the production of normal white blood cells (pink) Source: Wikimedia Commons Leukemia is a type of blood cancer generally characterized by the suppression of proper function …

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A Spoonful of (Modified) Sugar as an Antiviral Medicine

A Spoonful of (Modified) Sugar as an Antiviral Medicine

Figure 1: A negative stain transmission electron micrograph of Influenza virions Source: Wikimedia Commons Researchers at the University of Manchester have developed a new sugar-based virucidal medicine that is effective against a broad array of viruses (Jones et al., 2020). Cyclodextrins (also called CDs) are non-toxic cyclic glucose oligosaccharides produced as a result of starch …

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PANDAS––A Self-Destruction of the Mind

PANDAS––A Self-Destruction of the Mind

Figure 1: PANDAS, characterized by acute neurological and neuropsychiatric symptoms, was systematically reviewed by Sigra et al (2018) in hopes of encouraging further investigation towards the etiology and treatments associated with PANDAS and related disorders Source: Flickr Pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (PANDAS), pediatric acute-onset neuropsychiatric syndrome (PANS), childhood acute neuropsychiatric symptoms …

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The Next Source of Antibiotics: Viruses

The Next Source of Antibiotics: Viruses

Figure 1: A computer-generated image of a bacteriophage called a levivirus along with its mapped genome. The Lysis gene is also known as sgi and produces antibiotic proteins Source: Wikimedia Commons We have a crisis on our hands: bacteria are developing resistance to our most effective antibiotics. Many of these are inhibitors of proteins that …

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Defective Mitochondria Lead to Exhausted T Cells in the Tumor Microenvironment

Defective Mitochondria Lead to Exhausted T Cells in the Tumor Microenvironment

Figure 1: T cells (green, blue, and red) surround and prepare to kill a cancer cell (green and blue). Vesicles (shown in red) in the T cells contain perforin and granzymes, proteins that orchestrate the killing of target cells. This process of targeted cell destruction is compromised when mitochondria are rendered defective by excessive antigen …

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Why Young Investigators Should Consider Prehospital Care Research

Why Young Investigators Should Consider Prehospital Care Research

Figure 1: The author (14 hours and 10 patients into a 16-hour shift) killing time until his next resuscitation with an issue of Prehospital Emergency Care A car drifts across a double yellow line and slams into an oncoming tractor trailer.  A man collapses on the floor of a supermarket aisle after his heart suddenly …

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Blockchain Technology In COVID-19: A Brief Overview of Usage and Applications

Blockchain Technology In COVID-19: A Brief Overview of Usage and Applications

Figure 1: A visual representation of a blockchain transaction Source: Wikimedia Commons Blockchain is a specific type of database that serves as a digital record of monetary and non-monetary transactions. The blockchain system enables transactions through peer-to-peer (P2P) networks in the absence of mediating organizations, and it stores data in a highly secure framework known …

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Even When Out of Production, Oil and Gas Wells Wreak Havoc

Even When Out of Production, Oil and Gas Wells Wreak Havoc

Figure 1: An oil pumpjack at dusk Source: Pxhere In Autumn of 2014, a gas leak was discovered at Admiral King Elementary school in Ohio, forcing the school to temporarily close down and send their students to neighboring elementary schools. It took over a month for the source of the leak to be identified—an uncapped …

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