For that which is relating or is of the topic of Medicine
Figure 1: Smear preparation of bone marrow from a patient with multiple myeloma, the cancer of plasma cells Source: Wikimedia Commons Activated B lymphocytes, or plasma cells, are the only cells capable of secreting antibodies and thus play a critical role in mediating immune response to pathogens (D’Souza & Bhattacharya, 2019). The production of an …
Figure 1: The different ways a tumor can provide protection for itself through Treg (seen as circular, pink cells above) recruitment Source: Wikimedia Commons Researchers have discovered a potential new immunotherapy for certain tumors that involves downregulating a type of immune cell called Regulatory T Cells (or Tregs) in and around the target tumor. Tregs …
Figure 1: The human gut is home to a rich ecosystem of microbes. Recent research has highlighted the extent of viral diversification within the gut microbiome that has wide potential implications for human health Source: Pixabay Despite the intense focus on SARS-CoV-2, the ubiquity and diversity of viruses is extraordinary; after all they are the …
SARS-CoV-2 is not the only virus living among us Read More »
First Author: Jillian Troth1 Co-Authors [Alphabetical Order]: Caroline Conway1, Allison Kifer2, Vincent Lai4, Grace Lee3, Varun Lindagal1, Callie Moody1, and Melanie Prakash1 Dartmouth College1, University of California San Diego2, Williams College3, Rice University4 Figure 1: Fluorescent microscope imaging of neuroinflammation in wild-type mice, AD-model mice, and AD patient. Aggregation of amyloid precursor protein (red) indicates …
Exploring the Gut-Microbiota Hypothesis of Neurodegenerative Disease Pathogenesis Read More »
Figure 1: The image is taken from an elderly woman who has a type of acute myeloid leukemia in which the accumulation of immature blood-forming cells (purple) interferes with the production of normal white blood cells (pink) Source: Wikimedia Commons Leukemia is a type of blood cancer generally characterized by the suppression of proper function …
Bispecific Antibody Recruits Vγ9+ γδ T cells for Leukemia Treatment Read More »
Figure 1: A negative stain transmission electron micrograph of Influenza virions Source: Wikimedia Commons Researchers at the University of Manchester have developed a new sugar-based virucidal medicine that is effective against a broad array of viruses (Jones et al., 2020). Cyclodextrins (also called CDs) are non-toxic cyclic glucose oligosaccharides produced as a result of starch …
A Spoonful of (Modified) Sugar as an Antiviral Medicine Read More »
Figure 1: PANDAS, characterized by acute neurological and neuropsychiatric symptoms, was systematically reviewed by Sigra et al (2018) in hopes of encouraging further investigation towards the etiology and treatments associated with PANDAS and related disorders Source: Flickr Pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (PANDAS), pediatric acute-onset neuropsychiatric syndrome (PANS), childhood acute neuropsychiatric symptoms …
Figure 1: A computer-generated image of a bacteriophage called a levivirus along with its mapped genome. The Lysis gene is also known as sgi and produces antibiotic proteins Source: Wikimedia Commons We have a crisis on our hands: bacteria are developing resistance to our most effective antibiotics. Many of these are inhibitors of proteins that …
Figure 1: T cells (green, blue, and red) surround and prepare to kill a cancer cell (green and blue). Vesicles (shown in red) in the T cells contain perforin and granzymes, proteins that orchestrate the killing of target cells. This process of targeted cell destruction is compromised when mitochondria are rendered defective by excessive antigen …
Defective Mitochondria Lead to Exhausted T Cells in the Tumor Microenvironment Read More »
Figure 1: The author (14 hours and 10 patients into a 16-hour shift) killing time until his next resuscitation with an issue of Prehospital Emergency Care A car drifts across a double yellow line and slams into an oncoming tractor trailer. A man collapses on the floor of a supermarket aisle after his heart suddenly …
Why Young Investigators Should Consider Prehospital Care Research Read More »