Medicine

For that which is relating or is of the topic of Medicine

Could This Be the First Drug to Slow the Progression of Alzheimer’s

Could This Be the First Drug to Slow the Progression of Alzheimer’s?

Figure 1: A cross section of a model brain Source: unsplash.com Alzheimer’s Disease (AD) is a progressive, irreversible neurological condition that slowly destroys memory and cognitive skills and can be classified as either early or late onset. Most people diagnosed with Alzheimer’s develop symptoms in their mid-60s (late onset), whilst early onset Alzheimer’s is much rarer …

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Calling All CARs: Redesigning CAR-T Cancer Immunotherapy

Calling All CARs: Redesigning CAR-T Cancer Immunotherapy

Figure 1: This image displays microtubules – green fibre-like structures of the cell’s cytoskeleton – in human breast cancer tissue. Immunotherapy is a form of cancer treatment that induces the immune system to fight back against tumors. Although it has been a successful form of therapy, there are still several challenges that limit the effectiveness …

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Inactivation of Type I Interferon Necessary for Myeloid-Derived Suppressor Cells

Inactivation of Type I Interferon Necessary for Myeloid-Derived Suppressor Cells

Figure 1: IFNγ (purple, bottom) is one kind of interferon, which are proteins that are key in activating cells vital to the immune response. Upon inhibition of its pathway, by mechanisms like those to be described, activation of those cells fails and immunosuppressive conditions result Source: Wikimedia Commons Interferons are a class of molecules involved …

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Beginning stages of CRISPR detection in athletes Cover

Beginning stages of CRISPR detection in athletes

Figure 1: This image outlines CRISPR and its delivery mechanism. It has become a popular tool to combat diseases and improve crops, but it has also become a topic in ethical discussions. Such ethical discussions include the idea that athletes could soon have the ability to modify their genes to improve athleticism and gain an unfair …

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METMAP: Mapping metastatic progression

METMAP: Mapping metastatic progression

Figure 1: The start of metastasis – the movement of tumor cells from the initial site of tumor growth to other regions of the body Source: Wikimedia Commons Metastasis is an outcome that often turns treatable cancer into a fatal disease.  It occurs when circulating tumor cells acquire the ability to penetrate the walls of lymphatic or blood vessels; …

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The Microbiota-Gut-Brain Axis May Be the Missing Link Between Autism Spectrum Disorder and Anorexia Nervosa

The Microbiota-Gut-Brain Axis May Be the Missing Link Between Autism Spectrum Disorder and Anorexia Nervosa

Figure 1: The microbiota-gut-brain axis is a bidirectional pathway of communication between the enteric and central nervous systems. Shared abnormalities in MGB axis signaling may explain the comorbid overlaps between ASD and AN Source: created by the author via BioRender  Introduction The etiological paradigm for neurological disorders is currently shifting to one centered less on …

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A woman studying wildlife to identify different species. Originally shot as part of a promotion for the citizen science event “Loodusvaatluste maraton” where citizens focus on recognizing and identifying wildlife species in pre-designated areas

Beyond the White Coat Worker: An Overview of Citizen Science

By: Olivia Brado1, Luz Mariana Cumpa Gomez1, Shirin Dadina1, Katrina Miciek1, Priscilla Rubio1, and Elizabeth Schoemer1 1Trinity College, 2/14/21 Figure 1: A woman studying wildlife to identify different species. Originally shot as part of a promotion for the citizen science event “Loodusvaatluste maraton” where citizens focus on recognizing and identifying wildlife species in pre-designated areas …

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Factors in the Onset of Obesity – An American Public Health Crisis

Factors in the Onset of Obesity – An American Public Health Crisis

Figure 1: Obesity is typically diagnosed based on BMI. The different levels of obesity are shown here Source: Wikimedia Commons Introduction: Obesity is one of America’s greatest public health concerns. For both children and adults, rates of obesity have generally been on the rise since 1980 (Hales et al., 2018). In 1980, 4.8% of men …

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Anti-SLAMF7 Treatment for Multiple Myeloma by the Elimination of Immunosuppressive T Cells

Anti-SLAMF7 Treatment for Multiple Myeloma by the Elimination of Immunosuppressive T Cells

Figure 1: Smear preparation of bone marrow from a patient with multiple myeloma, the cancer of plasma cells Source: Wikimedia Commons Activated B lymphocytes, or plasma cells, are the only cells capable of secreting antibodies and thus play a critical role in mediating immune response to pathogens (D’Souza & Bhattacharya, 2019).  The production of an …

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Regulating Regulatory T Cells to Fight Cancer

Regulating Regulatory T Cells to Fight Cancer

Figure 1: The different ways a tumor can provide protection for itself through Treg (seen as circular, pink cells above) recruitment Source: Wikimedia Commons Researchers have discovered a potential new immunotherapy for certain tumors that involves downregulating a type of immune cell called Regulatory T Cells (or Tregs) in and around the target tumor. Tregs …

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